Jia En Kong
Milton Keynes Hospital, UKTitle: Survival Analysis of Lung Cancer patients in Brunei Darussalam
Abstract
Background: Cancer has been the most common
cause of deaths in Brunei Darussalam including lung cancer as one of the top
killers. This study presents the survival analysis of primary lung cancer
patients in Brunei Darussalam.
Methods: This was a retrospective cohort study
of a 15-year period (2002-2016) involving 797 primary lung cancer cases.
De-identified data extracted from Brunei Darussalam Cancer Registry was
analyzed using Kaplan-Meier method and log-rank test. Bonferroni corrections
were performed.
Results: 6 months, 1-year, 3-year, 5-year
survival rates of lung cancer patients were 62.2%, 51.0%, 38.0% and 34.7%
respectively. The median survival time was 12.4 months (95% Cl: 9.2, 15.7).
Patients diagnosed 2002-2006 had significant longer survival than patients
diagnosed 2007-2011(p=0.039) and those diagnosed 2011-2016 (p<0.001).
Survival time of patients diagnosed 2007-2011 was significantly longer than
patients diagnosed 2012-2016 (p=0.049). Patients with localised disease had
significantly longer survival time than patients with regional involvement
(p<0.001) and distal site involvement (p<0.001). Patients with distal
disease had significantly poorer survival rate than patients with regional
involvement (p<0.001). Patients aged 50 or above had significantly shorter
survival time than patients diagnosed at age 40-49 (p=0.003). There was no
significant difference between survival time of other demographic
characteristics.
Conclusions: The median survival time for lung
cancer patients in this study was 12.4 months. Early diagnosis, early stage of
cancer, and younger age were associated with longer survival time among lung
cancer patients in Brunei Darussalam.
Biography
Dr Jia En Kong completed her three year degree in Bachelor of Health Science (major in Medicine) in Universiti Brunei Darussalam, Brunei and continued with her medical education in the U.K. She graduated with Bachelor of Medicine, Bachelor of Surgey (BMBS) in the U.K. in 2022 and currently doing her foundation year 2 programme in Milton Keynes Univeristy Hospital, U.K.